Association between nasal polyps and novel inflammatory parameters

نویسندگان

  • Tayfun Apuhan
  • Gulali Aktas
  • Abant Izzet Baysal
چکیده

Nasal polyposis represents as a chronic hyperplastic sinusitis associated with chronic inflammation. In present retrospective study, we aimed to compare the Mean Platelet Volume (MPV), Red Cell Distribution Width (RDW) and Neutrophil to Lymphocyte Ratio (NLR) values of patients with nasal polyposis to those in healthy subjects. We included 35 nasal polyp patients and 45 healthy subjects into the study. White Blood Cell count (WBC), Neutrophil Count (NEU), Lymphocyte Count (LYM), Hemoglobin (Hb), Hematocrit (HTC), Mean Corpuscular Volume (MCV), RDW, Platelet Count (PLT) and MPV were recorded after obtaining from computerized database. There was statistically significant difference between study and control groups (p<0.001). Decreased MPV and elevated RDW and NLR are characteristics of nasal polyposis. These parameters may also be helpful in assessing the success of treatment. Further studies with a larger study population are needed to detect the possible correlation between MPV, RDW and NLR values in patients with nasal polyps.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Role of IgE Low-Affinity Receptor (CD23) in Pathogenesis of Nasal Polyp

Background: Nasal polyps, a common clinical problem, are characterized by eosinophilic and mast cell inflammation.  The role of allergy and IgE in pathogenesis of nasal polyps is still unclear.  IgE receptors are important components of the immunological pathway in allergic and inflammatory diseases. Objective: To determine if the low affinity IgE receptor (CD23) is presented on nasal polyp tis...

متن کامل

پلی‌مورفیسم ژن CD14 در بیماران مبتلا به پولیپوز بینی

Background: CD14 is known as a receptor for bacterial LPS (Lipopolysaccharides) and is followed by inflammatory reactions. This receptor on macrophage surface has a major role for recognition and clearance was happen without inflammatory reaction. Prolonged exposure to microbial products decreases the risk of allergic reactions. This is related to high level of CD14 in blood cells. Although the...

متن کامل

Inflammatory Septal Nasal Polyp

Introduction: Nasal polyps are benign prolapsed mucosal lesions which commonly arise from the paranasal sinuses and lateral walls of the nose especially the contact areas of osteomeatal complex. Though nasal polyps arising from the nasal septum have been reported, those arising from its anterior part are extremely rare and present a diagnostic dilemma.  Aetiology is multifactorial and is mainl...

متن کامل

Association of Mucosal Organisms with Patterns of Inflammation in Chronic Rhinosinusitis

BACKGROUND Chronic rhinosinusitis is a multifactorial process disease in which bacterial infection or colonization may play an important role in the initiation or persistence of inflammatory response. The association between mucosal bacteria presence and inflammatory patterns has only been partially explored. OBJECTIVE To demonstrate specific mucosal microorganisms possible association with i...

متن کامل

Evaluation of Usefulness of hs-CRP and Ferritin Assays in Patients with Nasal Polyps

BACKGROUND Chronic nature of the nasal polyps, tendency to recurrence, and lack of satisfying treatment need the diagnostic's parameters which show early inflammatory state as ferritin and hs-CRP. The Aim of Study. Assessment of hs-CRP and ferritin blood levels in nasal polyps patients in evaluation of treatment efficacy. METHODS All 38 patients were divided into 2 groups. Group I included 19...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2017